Do-Si-Dos by Medicann Seeds
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Do-Si-Dos is one of those strains that completely rewired the standard for indica-dominant hybrids when it dropped. Originally bred by ThaDocta over at Archive Seed Bank back in 2016, it was born from a desire to take the legendary but notoriously slow-vegging OGKB (OG Kush Breath) cut and give it some actual vigor. He hit it with his bulletproof Face Off OG male, and the resulting hybrid was nothing short of a masterpiece. Medicann Seeds took those genetics and ran with them, preserving that delicate balance of the sweet GSC lineage and the heavy, bone-crushing power of the OG.
In the grow room, this plant is an absolute stunner. It tends to stretch a bit during the flip, showing off its OG roots, but once it starts stacking, it throws down incredibly dense, resin-caked nugs that look like they've been rolled in sugar. Medicann's version holds true to the terpene profile that made the original so famous: a pungent mix of sweet mint, lime, and earthy pine, backed up by a sharp, fuel-like funk from the Face Off side. You’ll definitely want your carbon filters dialed in because the smell will easily punch through the walls of a tent by week six of flower.
As for the smoke, it’s a pure heavyweight experience. Regularly testing in the high 20s for THC, Do-Si-Dos delivers a "weighted blanket" effect that melts right into your bones. It starts with a brief, euphoric head rush before aggressively pulling you down into the couch. It’s the kind of high that genuinely helps with chronic pain and insomnia, which is exactly why it’s stayed in constant rotation for both medical patients and seasoned stoners. It’s not a daytime smoke by any stretch, but if you want a reliable, top-shelf knockout punch, this cut delivers every single time.
🏆 Legendary Foundation Strain
This is one of the most influential cannabis varieties in history. Do-Si-Dos has been used to breed 126 documented descendant strains in our database, making it a cornerstone of modern genetics.
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🧬 Explore the family: Do-Si-Dos · Pale Stranger · PBJ Breath · Starling Gloss · WiFi 43 x Dosidos #9 · Moonbow · Show Boat · Do-Si-Dos Cake · Archive Seed Bank - Pudding Pop
Ancestry Pedigree
Archive Seed Bank
Unknown or Legendary
Clone Only Strains
Unknown or Legendary
Unknown or Legendary
Dutch Passion
Original Strains
Unknown or Legendary
Clone Only Strains
Original Strains
Unknown or Legendary
Original Strains
Original Strains
Archive Seed Bank
Original Strains
Clone Only Strains
Clone Only Strains
Growing Do-Si-Dos: what to expect
As an indica-leaning plant, expect a modest stretch after the flip (roughly 50–100%) and dense bud structure — which makes late-flower humidity discipline the main risk: keep RH in the 40s once buds fatten to stay ahead of mold. Growers familiar with Do-Si-Dos will recognize much of its behavior. Whatever the listing says, the cut in YOUR tent is the ground truth: log feedings, readings, and photos, and let the trends — not the label — drive decisions.
Do-Si-Dos FAQ
How long does Do-Si-Dos take to flower?
Do-Si-Dos typically flowers in around 63 days after switching to a 12/12 light schedule. Individual phenotypes vary, so judge harvest readiness by trichome color, not the calendar.
Is Do-Si-Dos an indica or a sativa?
Do-Si-Dos is listed as mostly indica.
What are the parents of Do-Si-Dos?
Do-Si-Dos was bred from Do-Si-Dos by Medicann Seeds.
How strong is Do-Si-Dos?
Reported THC for Do-Si-Dos is 19% and CBD 0.4%. Actual potency depends heavily on environment, harvest ripeness, and cure quality.
What environment does Do-Si-Dos like?
Standard cannabis bands work well: VPD 0.8–1.1 kPa in veg and 1.0–1.4 kPa in flower, with humidity stepping down from 65–75% as a seedling to 40–50% in late flower. See the stage-by-stage table on this page.
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