Do-Si-Dos by Medicann Seeds

Do-Si-Dos strain photo
Type mostly indicaFlower ±63 daysTHC 19%Cross Do-Si-Dos

5 other breeders' versions of Do-Si-Dos — compare flowering times side by side →

Do-Si-Dos is one of those strains that completely rewired the standard for indica-dominant hybrids when it dropped. Originally bred by ThaDocta over at Archive Seed Bank back in 2016, it was born from a desire to take the legendary but notoriously slow-vegging OGKB (OG Kush Breath) cut and give it some actual vigor. He hit it with his bulletproof Face Off OG male, and the resulting hybrid was nothing short of a masterpiece. Medicann Seeds took those genetics and ran with them, preserving that delicate balance of the sweet GSC lineage and the heavy, bone-crushing power of the OG.

In the grow room, this plant is an absolute stunner. It tends to stretch a bit during the flip, showing off its OG roots, but once it starts stacking, it throws down incredibly dense, resin-caked nugs that look like they've been rolled in sugar. Medicann's version holds true to the terpene profile that made the original so famous: a pungent mix of sweet mint, lime, and earthy pine, backed up by a sharp, fuel-like funk from the Face Off side. You’ll definitely want your carbon filters dialed in because the smell will easily punch through the walls of a tent by week six of flower.

As for the smoke, it’s a pure heavyweight experience. Regularly testing in the high 20s for THC, Do-Si-Dos delivers a "weighted blanket" effect that melts right into your bones. It starts with a brief, euphoric head rush before aggressively pulling you down into the couch. It’s the kind of high that genuinely helps with chronic pain and insomnia, which is exactly why it’s stayed in constant rotation for both medical patients and seasoned stoners. It’s not a daytime smoke by any stretch, but if you want a reliable, top-shelf knockout punch, this cut delivers every single time.

🏆 Legendary Foundation Strain

This is one of the most influential cannabis varieties in history. Do-Si-Dos has been used to breed 126 documented descendant strains in our database, making it a cornerstone of modern genetics.

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BreederMedicann Seeds
Typemostly indica
Flowering time±63 days
THC19%
CBD0.4%
EnvironmentOutdoors, Greenhouse
LineageDo-Si-Dos
DescendantsPale Stranger, PBJ Breath, Starling Gloss, WiFi 43 x Dosidos #9, Moonbow, Show Boat, Do-Si-Dos Cake, Archive Seed Bank - Pudding Pop, Cog-ni-dos, Land Mine, Daiquiri OG, DDoS #33, Wifi 43 x Do-Si-Dos, PBJ, Super Sour Dosidos, Vetitum, 13th Floor, Black Ice Cream, Tire Fire, Dos Si Dos Auto, Peanut Butter Blossom, Peanut Butter Cookies, Peanut Butter Soda, Dosi Chunk, Do-Si-Dos, Peanut Butter N' Chocolate, Silver Blaze, Double Stuffed Sorbet, Brain Stroke Auto, Zoo Biscuits, San Fernando Valley OG x Do-Si-Dos, Peanut Butter OGKB, Peanut Butter Patties, Yakuza, Daisy Cutter, Peanutz, (GG#4 x BlissfulWizard) x Do-Si-Dos F2, Dosi Tree, The Gorgon, Jager Cookies, Dosidos #1, Donuts, Cherry Do-Si-Dos, Forbidos, Wild Horse, Hyper Fuel, Quartz Rock, Peanut Butter Power, Purple Dosi Punch, SmoreZ, Do-Sweet-Dos, Peanut Butter Breath, Flo-sidos, Do Si Dos Zkittlez, N.Y.S.O.M., Dirty Dozen, Wonder Weed, Dosi-Cake, Do Si Dos Auto, Do-Si-Dos, Uprising Seed Co - Dosi Fire, Mazar-i-Cake, DO-G, Rose Quartz, Do-Si-Dos, Dolato, Do Si Mints, Grapesidos, Dos Rodeos, Do Si Dos, Brain Cake, Smiley Face, Cookielato, Mesopotamian Mana, Nevada Mints, Jelly Breath, Do-Si-Dos OG, Dosidos X Birthday Cake, Double Dose, The Vault Seed Bank - Next level Dosidos, Peanut Butter Punch, Dosidos x Key Lime Pie, Dosidos x Watermelon Zkittlez, Spumoni, Double Cookies, ReDeux, Do-Si Pie, Toast-i-dos, Do-Si-Dos, Show Time, Hoe Down, Cookies Cream, Jon Woo, Dank Genetics - Sour Dosidos, Sugar Breath, Plum Wine, Ros'e, Heat Wave, Dosi Pop, Aj's cookies, Savage Hulk, Sweet Thang, Duct Tape, Double Dose, Butter Cookies, Dos Si Dos 33, OGKB V2.1, White Gold, PB Poundcake, Bubblewrap, Velvet Moon, Banana Dosi, Cake Bomb, Triple Chem Face, Gorilla Cookies, Caloosahatchee Kush, Purple Punch x Do-Si-Dos, Tag - A - Longs, Donkey Punch, Double Cookies Auto, Commodos, Dositopia, Auto Do-Si-Dos Cookies, Slurricane, Leonidos, Diesel Dough

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🧬 Explore the family: Do-Si-Dos · Pale Stranger · PBJ Breath · Starling Gloss · WiFi 43 x Dosidos #9 · Moonbow · Show Boat · Do-Si-Dos Cake · Archive Seed Bank - Pudding Pop

Ancestry Pedigree

Do-Si-Dos
Archive Seed Bank
OG Kush Breath
Unknown or Legendary
Girl Scout Cookies
Clone Only Strains
F1 Durban
Unknown or Legendary
Cherry Pie Kush
Unknown or Legendary
Durban Poison
Dutch Passion
Africa Sativa
Original Strains
Chem Dawg
Unknown or Legendary
OG Kush
Clone Only Strains
Thailand Sativa
Original Strains
Chem Dawg
Unknown or Legendary
Indica
Original Strains
Unknown Strain
Original Strains
Face Off OG BX1
Archive Seed Bank
Unknown Strain
Original Strains
OG Kush
Clone Only Strains
Face-Off OG Kush
Clone Only Strains

Growing Do-Si-Dos: what to expect

As an indica-leaning plant, expect a modest stretch after the flip (roughly 50–100%) and dense bud structure — which makes late-flower humidity discipline the main risk: keep RH in the 40s once buds fatten to stay ahead of mold. Growers familiar with Do-Si-Dos will recognize much of its behavior. Whatever the listing says, the cut in YOUR tent is the ground truth: log feedings, readings, and photos, and let the trends — not the label — drive decisions.

Do-Si-Dos FAQ

How long does Do-Si-Dos take to flower?

Do-Si-Dos typically flowers in around 63 days after switching to a 12/12 light schedule. Individual phenotypes vary, so judge harvest readiness by trichome color, not the calendar.

Is Do-Si-Dos an indica or a sativa?

Do-Si-Dos is listed as mostly indica.

What are the parents of Do-Si-Dos?

Do-Si-Dos was bred from Do-Si-Dos by Medicann Seeds.

How strong is Do-Si-Dos?

Reported THC for Do-Si-Dos is 19% and CBD 0.4%. Actual potency depends heavily on environment, harvest ripeness, and cure quality.

What environment does Do-Si-Dos like?

Standard cannabis bands work well: VPD 0.8–1.1 kPa in veg and 1.0–1.4 kPa in flower, with humidity stepping down from 65–75% as a seedling to 40–50% in late flower. See the stage-by-stage table on this page.

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Published by Cultivar (logmygrow.com), a structured grow journal. These reference bands are the same ones the app grades real grows against. Free to cite with a link. Some outbound product links are affiliate links — see disclosures.